Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806715 | 0.94 | TUBB4A (0.52) | ALDH1A1KDM4EMEN1HPGDMAPK1 | |
| SCHEMBL27930274 | 0.85 | FYN (0.53) | KITTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27912260 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2TUBB4A | |
| SCHEMBL31237224 | 0.83 | TUBB4A (0.56) | KITTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27930291 | 0.82 | PDGFRB (0.56) | KITTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27930282 | 0.81 | TUBB4A (0.61) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL27912259 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2KIT | |
| SCHEMBL28804998 | 0.78 | TUBB4A (0.58) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL28065501 | 0.77 | MGAM (0.51) | ALDH1A1MEN1MAPK1KMT2ATUBB4A | |
| SCHEMBL3846446 | 0.76 | PDE4A (0.49) | ALDH1A1KDM4EPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183640-B | Diaryl pyrazole azole compounds and preparation method thereof and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-103183640-B | Diaryl pyrazole azole compounds and preparation method thereof and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-103183640-A | Diaryl pyrazole compound, and preparation method and purpose thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-07-03 | — | — | CN | disclosed |