Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | SI | P14410 | 4/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930288 | 0.95 | MGAM (0.54) | MGAMGAASIMGAM2MAOB | |
| SCHEMBL27930282 | 0.85 | TUBB4A (0.61) | GAAMAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL28804998 | 0.81 | TUBB4A (0.58) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28821560 | 0.81 | GAA (0.47) | MGAMGAASIMGAM2MAOB | |
| SCHEMBL27930274 | 0.80 | FYN (0.53) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL1758642 | 0.78 | F2 (0.52) | MGAMGAASIMGAM2MAOB | |
| SCHEMBL27912263 | 0.77 | ALDH1A1 (0.50) | GAAMAPK1TUBB4ATUBBTUBA3C | |
| SCHEMBL27912260 | 0.76 | ALDH1A1 (0.50) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28306721 | 0.75 | GAA (0.47) | MGAMGAASIMGAM2MAOB | |
| SCHEMBL27930291 | 0.75 | PDGFRB (0.56) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183640-B | Diaryl pyrazole azole compounds and preparation method thereof and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-103183640-B | Diaryl pyrazole azole compounds and preparation method thereof and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-103183640-A | Diaryl pyrazole compound, and preparation method and purpose thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-07-03 | — | — | CN | disclosed |