SCHEMBL279126

SCHEMBL279126

CCN(CC)c1ccc(C=NN(c2ccccc2)c2ccc(CCO)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.53
GAA P10253 6/20 0.53
MAPK1 P28482 3/20 0.53
HTT P42858 3/20 0.53
ALDH1A1 P00352 13/20 0.49
KDM4E B2RXH2 9/20 0.49
ESRRG P62508 1/20 0.46
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
HPGD P15428 4/20 0.46
ALOX12 P18054 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
LMNA P02545 4/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
TDP1 Q9NUW8 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13657537 1.00 MAPT (0.53) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL278973 0.95 ALDH1A1 (0.54) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL13657541 0.95 ALDH1A1 (0.54) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL14448445 0.89 KMT2A (0.43) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL122070 0.88 MAPT (0.61) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL122069 0.88 MAPT (0.61) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL13681255 0.84 MAPT (0.47) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL14488628 0.84 ALDH1A1 (0.57) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL9493442 0.81 TSHR (0.63) MAPTGAAMAPK1HTTALDH1A1
SCHEMBL10105500 0.81 ALDH1A1 (0.56) MAPTGAAMAPK1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8142969-B2 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-03-27 US disclosed
US-8142969-B2 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-03-27 US disclosed
US-20070100164-A1 Arylamine processes XEROX CORPORATION (US) 2007-05-03 US disclosed
US-20070100164-A1 Arylamine processes XEROX CORPORATION (US) 2007-05-03 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US disclosed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070100164-A1 Arylamine processes AHR, INMT, TYR MAPT 1963/4885GAA 2516/4885MAPK1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.