SCHEMBL9493442

SCHEMBL9493442

CCN(Cc1ccccc1)c1ccc(C=NN(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.63
ALDH1A1 P00352 11/20 0.62
MAPT P10636 10/20 0.62
KDM4E B2RXH2 9/20 0.62
KMT2A Q03164 6/20 0.62
LMNA P02545 5/20 0.62
MAPK1 P28482 4/20 0.62
HPGD P15428 4/20 0.62
TDP1 Q9NUW8 4/20 0.62
MITF O75030 1/20 0.62
RAD52 P43351 1/20 0.62
L3MBTL1 Q9Y468 2/20 0.57
MEN1 O00255 5/20 0.55
MCL1 Q07820 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HTT P42858 3/20 0.54
ALOX12 P18054 3/20 0.54
G6PC1 P35575 4/20 0.54
GAA P10253 4/20 0.53
CNR2 P34972 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170198 0.91 ALDH1A1 (0.56) TSHRALDH1A1MAPTKDM4EKMT2A
SCHEMBL332653 0.91 ALDH1A1 (0.56) TSHRALDH1A1MAPTKDM4EKMT2A
SCHEMBL122070 0.90 MAPT (0.61) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL122069 0.90 MAPT (0.61) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL14337651 0.87 ALDH1A1 (0.72) TSHRALDH1A1MAPTKDM4EKMT2A
SCHEMBL1702643 0.83 ALDH1A1 (0.74) TSHRALDH1A1MAPTKDM4EKMT2A
SCHEMBL1056798 0.83 ALDH1A1 (0.74) TSHRALDH1A1MAPTKDM4EKMT2A
SCHEMBL14283653 0.81 MAPT (0.46) TSHRALDH1A1MAPTKDM4EKMT2A
SCHEMBL9775483 0.81 KMT2A (0.47) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL13657537 0.81 MAPT (0.53) ALDH1A1MAPTKDM4EKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5219689-A High durability, sensitivity MITSUBISHI PAPER MILLS LIMITED (JP) 1993-06-15 US disclosed