SCHEMBL279127

SCHEMBL279127

OCCc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(CCO)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
FFAR1 O14842 1/20 0.44
CA2 P00918 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MMP12 P39900 5/20 0.40
MAPKAPK2 P49137 1/20 0.39
CNR2 P34972 1/20 0.39
MMP13 P45452 4/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TAAR1 Q96RJ0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8076691 1.00 TDP1 (0.56) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL2312474 1.00 TDP1 (0.56) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL13992396 0.96 TDP1 (0.56) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL12960557 0.96 TDP1 (0.56) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL13992398 0.96 TDP1 (0.56) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL14371523 0.94 TDP1 (0.62) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL11119430 0.94 TDP1 (0.62) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL21303703 0.87 MEN1 (0.58) TDP1MEN1KMT2ACA2KDM4E
SCHEMBL12679110 0.86 CA2 (0.45) TDP1MEN1KMT2AFFAR1CA2
SCHEMBL8177188 0.86 TDP1 (0.48) TDP1MEN1KMT2AFFAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-20070100164-A1 Arylamine processes XEROX CORPORATION (US) 2007-05-03 US disclosed
US-20070100164-A1 Arylamine processes XEROX CORPORATION (US) 2007-05-03 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US disclosed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070100164-A1 Arylamine processes AHR, INMT, TYR TDP1 3264/4885MEN1 2288/4885KMT2A 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.