SCHEMBL279130

SCHEMBL279130

O=C(O)Cc1ccc(N(c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)c2ccc(CC(=O)O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.45
ABCC4 O15439 1/20 0.45
TSHR P16473 1/20 0.45
PTGS1 P23219 1/20 0.45
HTT P42858 1/20 0.45
PTGS2 P35354 2/20 0.44
CYP19A1 P11511 1/20 0.42
CYP11B2 P19099 1/20 0.42
NR3C1 P04150 1/20 0.42
FFAR1 O14842 1/20 0.41
GLO1 Q04760 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
SRD5A2 P31213 1/20 0.40
ESR1 P03372 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2210133 0.84 CYP19A1 (0.57) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL9608908 0.84 PTGS2 (0.45) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL10070915 0.83 PTGS2 (0.47) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL278974 0.83 CYP19A1 (0.46) LMNAGAATSHRPTGS2CYP19A1
SCHEMBL6032733 0.82 CYP19A1 (0.55) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL10128938 0.82 CYP19A1 (0.55) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL133557 0.82 CYP19A1 (0.55) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL7570019 0.82 CYP19A1 (0.55) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL14018365 0.82 CYP19A1 (0.55) LMNAGAAPTGS2CYP19A1CYP11B2
SCHEMBL6140273 0.82 CYP19A1 (0.55) LMNAGAAPTGS2CYP19A1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-20080008944-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2008-01-10 US disclosed
US-20080008944-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2008-01-10 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed