Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210133 | 0.85 | CYP19A1 (0.57) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL278974 | 0.84 | CYP19A1 (0.46) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL10070915 | 0.84 | PTGS2 (0.47) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL7752070 | 0.84 | PTGS2 (0.50) | PTGS2CYP19A1CYP11B2ESR1KMT2A | |
| SCHEMBL279130 | 0.84 | AKR1B1 (0.46) | PTGS2CYP19A1CYP11B2ESR1KMT2A | |
| SCHEMBL6032733 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL14018365 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL10128938 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL133557 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL7570019 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273517-B2 | Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge | FUJI XEROX CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120134713-A1 | METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE | FUJI XEROX CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |