Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139209 | 0.93 | MDM2 (0.51) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL8524430 | 0.91 | MDM2 (0.50) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL2409954 | 0.89 | MDM2 (0.49) | MDM2RAB9ANPC1KDM4EMAPT | |
| Carbamic Acid SCHEMBL29154176 | 0.82 | MDM2 (0.44) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL16175776 | 0.82 | MDM2 (0.44) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL4059081 | 0.81 | CYP1A2 (0.57) | MDM2RAB9ANPC1KDM4EMAPT | |
| Tetrahydrofuran SCHEMBL27422789 | 0.80 | MDM2 (0.43) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL27402049 | 0.79 | MDM2 (0.45) | MDM2RAB9ANPC1KDM4EMAPT | |
| Oxazole SCHEMBL27278480 | 0.77 | RAB9A (0.43) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL5947673 | 0.76 | CYP1A2 (0.54) | RAB9ANPC1CYP1A2CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249306-A | Intermediate compounds and processes for the preparation of quinoline derivatives such as laquinimod sodium | MAPI PHARMA LTD | 2013-08-14 | — | — | CN | disclosed |