Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524430 | 0.98 | MDM2 (0.50) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL2409954 | 0.95 | MDM2 (0.49) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL27913095 | 0.93 | MDM2 (0.47) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL16175776 | 0.88 | MDM2 (0.44) | MDM2RAB9ANPC1KDM4EMAPT | |
| Carbamic Acid SCHEMBL29154176 | 0.88 | MDM2 (0.44) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL4059081 | 0.87 | CYP1A2 (0.57) | MDM2RAB9ANPC1KDM4EMAPT | |
| Tetrahydrofuran SCHEMBL27422789 | 0.86 | MDM2 (0.43) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL27402049 | 0.85 | MDM2 (0.45) | MDM2RAB9ANPC1KDM4EMAPT | |
| Oxazole SCHEMBL27278480 | 0.83 | RAB9A (0.43) | MDM2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL5947673 | 0.82 | CYP1A2 (0.54) | RAB9ANPC1CYP1A2CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | claimed |
| CN-113272292-B | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2024-04-12 | — | — | CN | claimed |
| CN-111253384-B | Preparation and application of 3-isoxazole methoxy pyrazole-5-amide containing substituted phenyl isoxazole unit | 南通大学 | 2023-04-07 | — | — | CN | claimed |
| WO-2022245085-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2022-11-24 | — | — | WO | claimed |
| CN-111320715-B | Ultrahigh molecular weight polyolefin catalyst, and preparation method and application thereof | 叶平山 | 2022-10-04 | — | — | CN | claimed |
| CN-108350034-B | Antimicrobial polymyxin derived compounds | 莫纳什大学 | 2022-03-11 | — | — | CN | claimed |
| US-20220073461-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | WARSZAWSKI UNIWERSYTET MEDYCZNY (PL) | 2022-03-10 | — | — | US | claimed |
| EP-3908580-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | UNIWERSYTET JAGIELLONSKI (PL) | 2021-11-17 | — | — | EP | claimed |
| CN-113272292-A | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2021-08-17 | — | — | CN | claimed |
| CN-105263329-B | Methods and compositions for weed control | 孟山都技术公司 | 2020-09-18 | — | — | CN | claimed |
| US-20090325896-A1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | IBRAHIM PRABHA | 2009-12-31 | — | — | US | claimed |
| CN-100409748-C | Substituted phenyl-isoxazole herbicide | WANG ZHENGQUAN (CN) | 2008-08-13 | — | — | CN | claimed |
| CN-1939127-A | Substituted phenyl-isoxazole herbicide | WANG ZHENGQUAN (CN) | 2007-04-04 | — | — | CN | claimed |
| US-20060287275-A1 | Partial and full agonists of A1 adenosine receptors | IBRAHIM PRABHA | 2006-12-21 | — | — | US | claimed |
| US-6846934-B2 | Photochromic diarylethene substituted with isoxazole group | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-01-25 | — | — | US | claimed |
| US-20030118924-A1 | Diarylethene derivatives and photochromic thin film prepared using the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2003-06-26 | — | — | US | claimed |
| US-20030086978-A1 | Thermal stability, transparency, and photochromic property; to be used as optical materials such as an optical recording material, an optical switch, and the like | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2003-05-08 | — | — | US | claimed |
| US-20020188043-A1 | Photochromic diarylethene substituted with isoxazole group | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2002-12-12 | — | — | US | claimed |
| CN-1068567-A | NEW HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1993-02-03 | — | — | CN | claimed |
| US-3939167-A | 3-(2-Methylthio-2-tertiary aminoacetyl)-5-phenylisoxazoles | SHIONOGI & CO., LTD. (JA) | 1976-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325896-A1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | ADORA1, ADORA2A, ADORA3 | MDM2 2474/4885RAB9A 2024/4885NPC1 400/4885 |
| US-20060287275-A1 | Partial and full agonists of A1 adenosine receptors | ADORA1, ADORA2A, ADORA3 | MDM2 2474/4885RAB9A 2024/4885NPC1 400/4885 |
| US-20030118924-A1 | Diarylethene derivatives and photochromic thin film prepared using the same | DIAPH1, CRY1, CRY2 | MDM2 516/4885RAB9A 705/4885NPC1 1629/4885 |
| US-20220073461-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | TRPV5, P2RX5, TRPV1 | MDM2 4692/4885RAB9A 3675/4885NPC1 1107/4885 |
| US-20030086978-A1 | Thermal stability, transparency, and photochromic property; to be used as optical materials such as an optical recording material, an optical switch, and the like | CCNE2, CRYZ, TRRAP | MDM2 468/4885RAB9A 2072/4885NPC1 1067/4885 |
| US-20020188043-A1 | Photochromic diarylethene substituted with isoxazole group | CRY1, NR2E3, DDT | MDM2 3747/4885RAB9A 1531/4885NPC1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.