Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913502 | 0.90 | CAPN1 (0.43) | CAPN1GRB2CTSBOPRM1DPP4 | |
| SCHEMBL29394895 | 0.83 | CAPN1 (0.49) | CAPN1GRB2CTSBOPRM1ACE | |
| SCHEMBL30547998 | 0.83 | CAPN1 (0.48) | CAPN1CTSB | |
| SCHEMBL31218906 | 0.82 | GRB2 (0.51) | CAPN1GRB2CTSBOPRM1ACE | |
| SCHEMBL31042468 | 0.82 | OPRM1 (0.42) | CAPN1GRB2OPRM1ACEREN | |
| SCHEMBL29760981 | 0.81 | CAPN1 (0.57) | CAPN1GRB2CTSBOPRM1OPRD1 | |
| SCHEMBL32677766 | 0.81 | CAPN1 (0.48) | CAPN1CTSBOPRM1BDKRB2OPRD1 | |
| SCHEMBL32677764 | 0.81 | CAPN1 (0.48) | CAPN1CTSBOPRM1BDKRB2OPRD1 | |
| SCHEMBL31696320 | 0.81 | CTSD (0.45) | CAPN1GRB2OPRM1DPP4FAP | |
| SCHEMBL29511963 | 0.80 | ACE (0.46) | CAPN1GRB2OPRM1DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221410-A | GPR119 receptor modulators and treatment of disorders related thereto | ARENA PHARM INC | 2013-07-24 | — | — | CN | disclosed |