Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913486 | 0.90 | AGTR1 (0.48) | AGTR1AGTR2ALDH1A1MAPTMAPK1 | |
| SCHEMBL14229389 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2ALDH1A1MAPTMAPK1 | |
| SCHEMBL8555102 | 0.83 | AGTR1 (0.41) | AGTR1AGTR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14230028 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2ALDH1A1MAPTMAPK1 | |
| SCHEMBL9233853 | 0.80 | AGTR1 (0.59) | AGTR1AGTR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14200703 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2ALDH1A1MAPTMAPK1 | |
| SCHEMBL27913490 | 0.77 | TXNRD1 (0.39) | AGTR1AGTR2ALDH1A1MAPTMAPK1 | |
| SCHEMBL28475797 | 0.76 | ALDH1A1 (0.38) | AGTR1AGTR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28450709 | 0.74 | POLB (0.41) | ALDH1A1MAPTVCAM1GSRTXNRD1 | |
| SCHEMBL9854360 | 0.74 | AGTR1 (0.59) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242225-A | Picolinate amino pyridine compound and preparation method thereof | HUNAN RES INST CHEMICAL IND | 2013-08-14 | — | — | CN | claimed |