Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403546 | 0.85 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6HCRTR1HCRTR2 | |
| SCHEMBL2713663 | 0.85 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6HCRTR1HCRTR2 | |
| SCHEMBL796410 | 0.83 | L3MBTL1 (0.60) | EPHX2L3MBTL1JMJD6GABRA5MAPT | |
| SCHEMBL13875980 | 0.82 | EPHX2 (0.50) | EPHX2L3MBTL1JMJD6HCRTR1HCRTR2 | |
| SCHEMBL30281370 | 0.82 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6GSK3BMAPT | |
| SCHEMBL13890805 | 0.81 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6HCRTR1HCRTR2 | |
| SCHEMBL2799836 | 0.80 | KCNK3 (0.48) | L3MBTL1MAPTPOLBMEN1KMT2A | |
| SCHEMBL31191107 | 0.79 | EPHX2 (0.53) | EPHX2L3MBTL1JMJD6HCRTR1HCRTR2 | |
| SCHEMBL29227517 | 0.78 | DDR1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Nitrous Acid SCHEMBL28864182 | 0.78 | L3MBTL1 (0.55) | EPHX2L3MBTL1JMJD6GABRA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478497-A | Aryl amine derivatives as TTX S blocker | 拉夸里亚创药株式会社 | 2017-03-08 | — | — | CN | disclosed |
| CN-103249721-B | Arylamine Derivatives as TTX-S Blockers | 拉夸里亚创药株式会社 | 2016-10-12 | — | — | CN | disclosed |
| CN-103249721-A | Arylamine Derivatives as TTX-S Blockers | RAQUALIA PHARMA INC | 2013-08-14 | — | — | CN | disclosed |