Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796410 | 0.86 | L3MBTL1 (0.60) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL2713663 | 0.84 | EPHX2 (0.52) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL30403546 | 0.84 | EPHX2 (0.52) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL28864180 | 0.82 | EPHX2 (0.48) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL13875980 | 0.82 | EPHX2 (0.50) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL31191107 | 0.82 | EPHX2 (0.53) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL27913659 | 0.82 | EPHX2 (0.50) | EPHX2L3MBTL1POLBMAPK1MAPT | |
| SCHEMBL20916908 | 0.81 | ABL1 (0.42) | HDAC1HDAC6MAPK1MAPTOPRK1 | |
| SCHEMBL31696416 | 0.81 | ABL1 (0.42) | HDAC1HDAC6MAPK1MAPTOPRK1 | |
| Nitrous Acid SCHEMBL28864182 | 0.81 | L3MBTL1 (0.55) | EPHX2L3MBTL1POLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |