Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890805 | 0.87 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6MAPTGSK3B | |
| SCHEMBL796410 | 0.83 | L3MBTL1 (0.60) | EPHX2L3MBTL1JMJD6MAPTPOLB | |
| SCHEMBL2713663 | 0.82 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6MAPTGSK3B | |
| SCHEMBL30281370 | 0.82 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6MAPTGSK3B | |
| SCHEMBL30403546 | 0.82 | EPHX2 (0.52) | EPHX2L3MBTL1JMJD6MAPTGSK3B | |
| SCHEMBL27913659 | 0.79 | EPHX2 (0.50) | EPHX2L3MBTL1JMJD6MAPTGSK3B | |
| SCHEMBL13875980 | 0.79 | EPHX2 (0.50) | EPHX2L3MBTL1JMJD6MAPTGSK3B | |
| SCHEMBL31191259 | 0.79 | ALDH1A1 (0.41) | EPHX2L3MBTL1JMJD6ACHEMAPT | |
| Nitrous Acid SCHEMBL28864182 | 0.78 | L3MBTL1 (0.55) | EPHX2L3MBTL1JMJD6MAPTPOLB | |
| SCHEMBL28864180 | 0.77 | EPHX2 (0.48) | EPHX2L3MBTL1JMJD6MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702025-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024223715-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-31 | — | — | WO | disclosed |