SCHEMBL279141

SCHEMBL279141

Cc1ccc(N(c2ccc(CCCC(=O)O)cc2)c2ccc(-c3ccc(-c4ccc(N(c5ccc(CCCC(=O)O)cc5)c5ccc(C)c(C)c5)cc4)cc3)cc2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 2/20 0.48
GMNN O75496 1/20 0.48
LMNA P02545 1/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
GABRA1 P14867 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48
THPO P40225 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
PMP22 Q01453 1/20 0.48
HIF1A Q16665 1/20 0.48
SLCO1B3 Q9NPD5 1/20 0.48
HSD17B10 Q99714 1/20 0.47
RXRA P19793 2/20 0.46
RXRB P28702 2/20 0.46
RXRG P48443 2/20 0.46
HDAC3 O15379 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607497 0.96 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6
SCHEMBL12316349 0.91 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6
SCHEMBL279140 0.89 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6
SCHEMBL14732615 0.87 FFAR1 (0.48) ALDH1A1LMNAFFAR1
SCHEMBL14732631 0.86 FFAR1 (0.50) ALDH1A1LMNAFFAR1
SCHEMBL15233008 0.86 FFAR4 (0.41) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6
SCHEMBL437661 0.86 RARB (0.43) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6
SCHEMBL12404415 0.83 RARB (0.41) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6
SCHEMBL2260320 0.83 RARB (0.45) ALDH1A1CYP2D6MAPTTSHRHSD17B10
SCHEMBL15277868 0.83 FFAR1 (0.64) SMN1; SMN2ALDH1A1GMNNLMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-7892717-B2 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2011-02-22 US disclosed
US-7892717-B2 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2011-02-22 US disclosed
US-7887981-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers, a photosensitive layer and protective coatings comprising curable resins; durability FUJI XEROX CO., LTD. (JP) 2011-02-15 US disclosed
US-20080008944-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2008-01-10 US disclosed
US-20080008944-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2008-01-10 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed