SCHEMBL279140

SCHEMBL279140

Cc1ccc(N(c2ccc(CCCC(=O)O)cc2)c2ccc(-c3ccc(N(c4ccc(CCCC(=O)O)cc4)c4ccc(C)c(C)c4)c(C)c3)cc2C)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GMNN O75496 1/20 0.43
LMNA P02545 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
GABRA1 P14867 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
THPO P40225 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
PMP22 Q01453 1/20 0.43
HIF1A Q16665 1/20 0.43
SLCO1B3 Q9NPD5 1/20 0.43
RARB P10826 1/20 0.43
HSD17B10 Q99714 2/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437661 0.97 RARB (0.43) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL15233008 0.97 FFAR4 (0.41) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL12404415 0.94 RARB (0.41) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL14732625 0.93 FFAR1 (0.44) ALDH1A1LMNARARBRXRARXRB
SCHEMBL25994062 0.90 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL279141 0.89 SMN1; SMN2 (0.48) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL14732618 0.86 FFAR1 (0.49) LMNARARBRXRARXRBRXRG
SCHEMBL9607497 0.85 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL279458 0.85 RARB (0.38) ALDH1A1CYP2D6RARBMCL1
SCHEMBL7208250 0.85 RARB (0.42) ALDH1A1SMN1; SMN2CYP2D6TSHRRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230259048-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, ELECTROPHOTOGRAPHIC APPARATUS, PROCESS CARTRIDGE, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-20230259047-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-20230259047-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-10935898-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-03-02 US disclosed
US-9280073-B1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2016-03-08 US disclosed
US-9152120-B2 Cleaning blade, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-10-06 US disclosed
US-9075326-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-07-07 US disclosed
US-9023563-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-05-05 US disclosed
US-8956794-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-17 US disclosed
US-8895216-B2 Image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-11-25 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed