Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915315 | 1.00 | CTSB (0.50) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL11132299 | 0.86 | POLB (0.51) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL805204 | 0.86 | POLB (0.51) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL11132296 | 0.86 | POLB (0.51) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL28068999 | 0.86 | L3MBTL1 (0.56) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL9828630 | 0.83 | TACR1 (0.58) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL27670131 | 0.83 | GRIA2 (0.54) | CTSLFOLH1ACECTBP2 | |
| SCHEMBL2320119 | 0.83 | GRIA2 (0.54) | CTSLFOLH1ACECTBP2 | |
| SCHEMBL22290967 | 0.83 | SLC1A1 (0.57) | CTSSCTSKPPARGPPARAFOLH1 | |
| SCHEMBL6217362 | 0.82 | CTSB (0.57) | CTSBPOLBCTSLCTSSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102481330-B | Variants of C-type natriuretic peptide | BIOMARIN PHARM INC | 2014-12-10 | — | — | CN | disclosed |
| CN-101600700-B | Novel 2-amino oxazolines as TAAR1 ligands for CNS disorders | HOFFMANN LA ROCHE | 2013-08-21 | — | — | CN | disclosed |