Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210815 | 0.90 | PTPN1 (0.50) | TTRESR1TDP1PTPN1PTPN2 | |
| SCHEMBL1191123 | 0.82 | TTR (0.58) | TTRESR1TSHRCYP3A4TDP1 | |
| SCHEMBL29379505 | 0.77 | ESR1 (0.49) | ESR1SLC22A12MAPTHPGDALOX15 | |
| SCHEMBL3626525 | 0.77 | TTR (0.57) | TTRESR1TSHRCYP3A4TDP1 | |
| SCHEMBL2070727 | 0.76 | GSK3B (0.38) | MEN1ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL10498467 | 0.76 | KDM4E (0.54) | ESR1TDP1HSD17B10ALDH1A1MAPT | |
| SCHEMBL4458695 | 0.75 | TTR (0.68) | TTRESR1TSHRCYP3A4TDP1 | |
| SCHEMBL11056394 | 0.75 | OGG1 (0.34) | TTRTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL2978780 | 0.73 | CA12 (0.52) | CYP3A4TDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL28885871 | 0.73 | TTR (0.65) | TTRESR1TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256252-B | Acetophenone compound, preparation method and application in preparing medicine for treating cancer | 西北农林科技大学 | 2021-08-27 | — | — | CN | claimed |
| CN-105503788-B | The substitution of one kind 3 the third 2 ketone compounds of alkene 1 and its application | 中国人民解放军第二军医大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-103044231-A | Preparation method of 3, 5-dibromo-2, 4-dihydroxyacetophenone | UNIV XUZHOU NORMAL | 2013-04-17 | — | — | CN | disclosed |
| CN-103044231-A | Preparation method of 3, 5-dibromo-2, 4-dihydroxyacetophenone | UNIV XUZHOU NORMAL | 2013-04-17 | — | — | CN | disclosed |