Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 3/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536837 | 0.84 | AKR1C3 (0.41) | ALPLPLAAALPGMAPTSNCA | |
| SCHEMBL12709966 | 0.82 | ESR1 (0.55) | ESR1ALOX15GUSBALPLPLAA | |
| SCHEMBL31509307 | 0.81 | CA12 (0.58) | ESR1ALPLPLAAALPGMAPT | |
| SCHEMBL105705 | 0.81 | CA12 (0.58) | ESR1ALPLPLAAALPGMAPT | |
| SCHEMBL27769961 | 0.79 | CA12 (0.56) | ESR1ALPLPLAAALPGMAPT | |
| SCHEMBL29748630 | 0.79 | ALDH1A1 (0.53) | ESR1ALOX15SLC22A12PKMHPGD | |
| SCHEMBL28037289 | 0.78 | CES2 (0.41) | HPGD | |
| SCHEMBL30436340 | 0.77 | CA12 (0.64) | ESR1ALOX15HPGDMAPTSNCA | |
| SCHEMBL312791 | 0.77 | CA12 (0.64) | ESR1ALOX15HPGDMAPTSNCA | |
| SCHEMBL27915966 | 0.77 | TTR (0.58) | ESR1ALOX15SLC22A12HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192454-A1 | COMPOSITIONS FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022031838-A1 | COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2022-02-10 | — | — | WO | disclosed |