Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209085 | 1.00 | ADRB3 (0.62) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL15995630 | 0.83 | ADRB2 (0.69) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL17209086 | 0.82 | NAMPT (0.53) | ADRB3ADRB1 | |
| SCHEMBL17209087 | 0.82 | NAMPT (0.53) | ADRB3ADRB1 | |
| SCHEMBL4867710 | 0.82 | ADRB2 (0.60) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL4863250 | 0.82 | ADRB2 (0.60) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL7042995 | 0.80 | DRD2 (0.59) | SMN1; SMN2 | |
| SCHEMBL19245597 | 0.80 | ADRB2 (0.67) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL19245648 | 0.80 | ADRB2 (0.67) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL25159567 | 0.78 | GLS (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111165-A | Merariveron preparation method | UNIV HENAN NORMAL | 2015-12-02 | — | — | CN | claimed |
| CN-105111165-A | Merariveron preparation method | UNIV HENAN NORMAL | 2015-12-02 | — | — | CN | disclosed |
| CN-103232352-A | (R)-4-(2-(2-hydroxyl-2-phenylethylamino)-ethyl) tert-butyl phenylcarbamate | SUZHOU UUGENE BIOPHARMA CO LTD | 2013-08-07 | — | — | CN | disclosed |
| CN-103232352-A | (R)-4-(2-(2-hydroxyl-2-phenylethylamino)-ethyl) tert-butyl phenylcarbamate | SUZHOU UUGENE BIOPHARMA CO LTD | 2013-08-07 | — | — | CN | disclosed |