Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.58 |
| ▸ | SPR | P35270 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ELOVL6 | Q9H5J4 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689403 | 0.87 | HTR2A (0.55) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL14413086 | 0.87 | HTR2A (0.55) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL4771117 | 0.87 | SPR (0.48) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL4106774 | 0.85 | HTR2A (0.56) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL2928335 | 0.85 | ELOVL6 (0.45) | HTR2ASPRKCNH2HTR2CALDH1A1 | |
| SCHEMBL2634144 | 0.85 | SPR (0.44) | HTR2ASPRKCNH2HTR2C | |
| SCHEMBL2931624 | 0.85 | SPR (0.53) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL5428002 | 0.85 | CA12 (0.44) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL23799261 | 0.84 | SPR (0.46) | HTR2ASPRKCNH2HTR2CDRD2 | |
| SCHEMBL4539607 | 0.84 | SPR (0.46) | HTR2ASPRKCNH2HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |