Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917812 | 0.84 | HTR2A (0.58) | SPRHTR2AAKR1C3ALDH1A1HTR2C | |
| SCHEMBL23799261 | 0.83 | SPR (0.46) | SPRHTR2AAKR1C3ALDH1A1HTR2C | |
| SCHEMBL2634144 | 0.82 | SPR (0.44) | SPRL3MBTL3HTR2AL3MBTL1HTR2C | |
| SCHEMBL3846739 | 0.82 | MBTD1 (0.48) | L3MBTL3MBTD1HTR2AL3MBTL1AKR1C3 | |
| SCHEMBL29711772 | 0.82 | MBTD1 (0.48) | L3MBTL3MBTD1HTR2AL3MBTL1AKR1C3 | |
| SCHEMBL265483 | 0.81 | SMN1; SMN2 (0.55) | HTR2AHTR2CKCNH2MMP2 | |
| SCHEMBL17907549 | 0.80 | CTSL (0.61) | ALDH1A1ATMCTSLCTSKCTSB | |
| SCHEMBL1498303 | 0.80 | CNR1 (0.51) | CA1CA2MMP2CTSS | |
| SCHEMBL12334568 | 0.79 | MBTD1 (0.49) | L3MBTL3MBTD1HTR2AL3MBTL1AKR1C3 | |
| SCHEMBL19510910 | 0.79 | MBTD1 (0.49) | L3MBTL3MBTD1HTR2AL3MBTL1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286789-A1 | Bi-Aryl Meta-Pyrimidine Inhibitors of Kinases | TARGEGEN, INC. (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286789-A1 | Bi-Aryl Meta-Pyrimidine Inhibitors of Kinases | JAK2, TYK2, LTK | SPR 1295/4885L3MBTL3 3149/4885MBTD1 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.