Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.60 |
| ▸ | ACACB | O00763 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917924 | 0.86 | ALDH1A1 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10080945 | 0.86 | BCHE (0.58) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL10194489 | 0.84 | ACACB (0.71) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL4007519 | 0.83 | HDAC3 (0.71) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL8208140 | 0.83 | HDAC3 (0.78) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL6584417 | 0.83 | HDAC3 (0.78) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL4007525 | 0.83 | HDAC3 (0.71) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL27900201 | 0.82 | CCR8 (0.53) | ALDH1A1PKMLMNATGFBR1GBA1 | |
| SCHEMBL27917918 | 0.82 | MGLL (0.51) | BCHEMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL2097769 | 0.81 | KMT2A (0.65) | F10ALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |