Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917867 | 0.89 | MEN1 (0.38) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27936354 | 0.88 | — | — | |
| SCHEMBL27936378 | 0.88 | NAMPT (0.31) | — | |
| SCHEMBL27917863 | 0.87 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL27917869 | 0.85 | TMEM97 (0.42) | KMT2AHSD17B3 | |
| SCHEMBL27917858 | 0.82 | MEN1 (0.38) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27936267 | 0.81 | DRD2 (0.31) | — | |
| SCHEMBL9809180 | 0.73 | MEN1 (0.37) | ALDH1A1MEN1KMT2AHDAC3HSD17B3 | |
| SCHEMBL27936399 | 0.71 | MEN1 (0.33) | MEN1KMT2AHDAC3 | |
| SCHEMBL27936286 | 0.71 | MEN1 (0.33) | MEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254172-A | Cytoskeletal active rho kinase inhibitor compounds, composition and use | INSPIRE PHARMACEUTICALS INC | 2013-08-21 | — | — | CN | disclosed |