Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22411030 | 0.72 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9809180 | 0.70 | MEN1 (0.37) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL22411031 | 0.68 | TAS1R3 (0.38) | MEN1KMT2ASMN1; SMN2RAB9AMAPT | |
| SCHEMBL5141014 | 0.67 | HDAC3 (0.37) | MEN1KMT2A | |
| SCHEMBL1128432 | 0.67 | HDAC3 (0.35) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL324667 | 0.66 | P2RX4 (0.48) | SMN1; SMN2RAB9AALDH1A1MAPTATM | |
| Iodide SCHEMBL10822526 | 0.65 | HDAC3 (0.35) | MEN1KMT2A | |
| SCHEMBL14890911 | 0.62 | TAS1R3 (0.45) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL28171516 | 0.61 | KDM4E (0.56) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30579890 | 0.59 | SIGMAR1 (0.47) | MEN1KMT2ARAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254172-A | Cytoskeletal active rho kinase inhibitor compounds, composition and use | INSPIRE PHARMACEUTICALS INC | 2013-08-21 | — | — | CN | disclosed |