Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917854 | 0.85 | PRMT5 (0.31) | KMT2AHSD17B3 | |
| SCHEMBL27917867 | 0.82 | MEN1 (0.38) | KMT2A | |
| SCHEMBL27917858 | 0.81 | MEN1 (0.38) | SIGMAR1KCNH2KMT2A | |
| SCHEMBL27936354 | 0.81 | — | — | |
| SCHEMBL27936378 | 0.81 | NAMPT (0.31) | — | |
| SCHEMBL27936267 | 0.81 | DRD2 (0.31) | — | |
| SCHEMBL27917863 | 0.80 | PRMT5 (0.36) | TMEM97SIGMAR1KCNH2 | |
| SCHEMBL9809180 | 0.69 | MEN1 (0.37) | TMEM97SIGMAR1KCNH2KMT2AHSD17B3 | |
| SCHEMBL27936399 | 0.68 | MEN1 (0.33) | KMT2A | |
| SCHEMBL27936286 | 0.68 | MEN1 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254172-A | Cytoskeletal active rho kinase inhibitor compounds, composition and use | INSPIRE PHARMACEUTICALS INC | 2013-08-21 | — | — | CN | disclosed |