Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936532 | 0.81 | APLNR (0.43) | APLNRESR1ESR2USP7 | |
| SCHEMBL17044891 | 0.81 | APLNR (0.43) | APLNRESR1ESR2USP7 | |
| SCHEMBL12276078 | 0.81 | APLNR (0.43) | APLNRESR1ESR2USP7 | |
| SCHEMBL11069038 | 0.75 | ESR1 (0.40) | APLNRESR1ESR2 | |
| SCHEMBL2757603 | 0.74 | APLNR (0.36) | APLNR | |
| SCHEMBL10105660 | 0.74 | APLNR (0.58) | APLNR | |
| SCHEMBL27342375 | 0.74 | APLNR (0.41) | APLNR | |
| SCHEMBL25317850 | 0.74 | APLNR (0.42) | APLNRESR1ESR2 | |
| SCHEMBL2063215 | 0.72 | APLNR (0.34) | APLNR | |
| SCHEMBL2625465 | 0.72 | PTGS1 (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158795-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2023-07-06 | — | — | US | disclosed |
| EP-3967682-A1 | BISHETEROCYCLIC CARBONYL SUBSTITUTED DIHYDROPYRAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2022-03-16 | — | — | EP | disclosed |
| WO-2022048605-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATIONS | 南昌奥瑞药业有限公司 | 2022-03-10 | — | — | WO | disclosed |
| US-20180338980-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-29 | — | — | US | disclosed |
| US-10023562-B2 | Heteroaryl substituted pyridyl compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| US-10023562-B2 | Heteroaryl substituted pyridyl compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| WO-2018112077-A1 | INHIBITORS OF DIHYDROCERAMIDE DESATURASE FOR TREATING DISEASE | CENTAURUS THERAPEUTICS (US) | 2018-06-21 | — | — | WO | disclosed |
| EP-3307715-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2018-04-18 | — | — | EP | disclosed |
| CN-107848974-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2018-03-27 | — | — | CN | disclosed |
| US-4686290-A | Preparation of pyrimidyl phosphoric acid derivatives and intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0222210-A2 | Process for preparing phosphoric-acid derivatives and intermediates | BAYER AG (DE) | 1987-05-20 | — | — | EP | disclosed |
| US-4665175-A | FROM 4-CHLORO-5-BENZYLOXYPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |
| US-4654329-A | Insecticidal, miticidal or nematocidal phosphorus esters of 5-pyrimidinols | THE DOW CHEMICAL COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0167893-A1 | Process for preparing phosphoric-acid derivatives and intermediate compounds | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0167888-A1 | Process for preparing phosphoric-acid derivatives and intermediate compounds | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0128350-A2 | Pyrimidylphosphoric-acid derivatives and their use as pesticides | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4486422-A | SYSTEMIC | THE DOW CHEMICAL COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| US-4429125-A | INSECTICIDES FOR APPLICATION TO SOILS | THE DOW CHEMICAL CO. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4127652-A | ARTHROPODICIDE, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | APLNR 1270/4885ESR1 4699/4885ESR2 3523/4885 |
| US-10023562-B2 | Heteroaryl substituted pyridyl compounds useful as kinase modulators | IRAK4, IRAK3, IRAK2 | APLNR 3247/4885ESR1 1687/4885ESR2 2756/4885 |
| US-20180338980-A1 | AROMATIC SULFONAMIDE DERIVATIVES | ARSA, SULT2A1, TPST2 | APLNR 3487/4885ESR1 1890/4885ESR2 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.