Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31521437 | 0.86 | PDE2A (0.41) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL9967747 | 0.83 | GABRA1 (0.44) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL28758952 | 0.79 | CYP3A4 (0.39) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL16953380 | 0.79 | CYP1A2 (0.39) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL17553331 | 0.79 | CYP3A4 (0.39) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL24039916 | 0.79 | CYP1A2 (0.39) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL30202466 | 0.79 | PNMT (0.64) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL14121111 | 0.79 | PNMT (0.64) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL28361634 | 0.79 | CYP3A4 (0.39) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL25665348 | 0.79 | CES2 (0.37) | CYP3A4CYP1A2LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096957-A1 | RAS-PI3K INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-107794282-A | A kind of gram of azoles replaces the preparation method and bacterial strain of Buddhist nun's chiral intermediate | 浙江工业大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-103319311-A | Preparation method of crizotinib intermediate (1S)-1-(2, 6-dichloro-3-fluorophenyl)ethanol | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-09-25 | — | — | CN | disclosed |