Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851636 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAATSHRACHESMN1; SMN2 | |
| SCHEMBL28134802 | 0.81 | TDP1 (0.50) | GAAACHEEPHX1 | |
| SCHEMBL28316794 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ACHESMN1; SMN2EPHX1 | |
| SCHEMBL28244485 | 0.80 | GAA (0.37) | ALDH1A1GAAKDM4EACHE | |
| SCHEMBL27766308 | 0.80 | ACHE (0.35) | ALDH1A1GAAMAPK1KDM4ETSHR | |
| SCHEMBL28032152 | 0.79 | ZDHHC20 (0.42) | ALDH1A1GAAMAPK1TSHRACHE | |
| SCHEMBL27872670 | 0.78 | ACHE (0.38) | ACHEEPHX1 | |
| SCHEMBL14486890 | 0.78 | MAPK1 (0.50) | ALDH1A1GAAMAPK1KDM4EHIF1A | |
| SCHEMBL21579178 | 0.76 | MAPK1 (0.43) | ALDH1A1GAAMAPK1KDM4EHIF1A | |
| SCHEMBL27540075 | 0.76 | ALDH1A1 (0.36) | ALDH1A1GAAMAPK1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103328442-A | Azetidine derivatives useful for the treatment of metabolic and inflammatory diseases | GALAPAGOS NV | 2013-09-25 | — | — | CN | disclosed |