Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 8/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405232 | 0.84 | PTGS2 (0.45) | HCAR2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL1484347 | 0.82 | EPHX1 (0.44) | HCAR2VNN1CYP19A1TDP1 | |
| SCHEMBL1808417 | 0.82 | HCAR2 (0.38) | HCAR2VNN1CYP19A1 | |
| SCHEMBL27541431 | 0.80 | PTGS2 (0.47) | AKR1C3AKR1C2 | |
| SCHEMBL1808418 | 0.74 | HCAR2 (0.34) | HCAR2CYP19A1 | |
| SCHEMBL27485847 | 0.74 | APP (0.42) | HCAR2VNN1CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL27654722 | 0.74 | HCAR2 (0.47) | HCAR2RAB9A | |
| SCHEMBL27492286 | 0.74 | CYP19A1 (0.52) | CYP19A1AKR1C3AKR1C2CYP17A1POLB | |
| SCHEMBL27832415 | 0.73 | FFAR2 (0.33) | NPC1RAB9APOLB | |
| SCHEMBL27836776 | 0.73 | HDAC1 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130792-B | A kind of thiazolamine compounds | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-103130792-A | 2-aminothiazoles compound | JIANGSU CHIA TAI TIANQING PHAR | 2013-06-05 | — | — | CN | disclosed |