SCHEMBL2792437

COC[C@H]1C[C@H]2[C@@H]3CC[C@H](COC)[C@@]3(C)CC[C@@H]2[C@@]2(C)C(O[Si](C)(C)C(C)(C)C)CCC[C@H]12

nearest known ligand 0.33

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	PPM1D	O15297	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4340290	0.75	ESR1 (0.39)	—
SCHEMBL7296339	0.75	ESR1 (0.39)	—
SCHEMBL7296749	0.72	CYP19A1 (0.38)	PPM1D
SCHEMBL7288543	0.70	PPM1D (0.35)	PPM1D
SCHEMBL2793171	0.66	SHBG (0.49)	—
SCHEMBL2793175	0.66	SHBG (0.49)	—
SCHEMBL3114166	0.65	CYP17A1 (0.34)	—
SCHEMBL3118663	0.64	GABRA1 (0.49)	—
SCHEMBL24568162	0.64	LMNA (0.33)	PPM1D
SCHEMBL7777982	0.62	CYP3A4 (0.41)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010149666-A1	METHODS FOR TREATING NEOPLASIA	MEDEXIS S.A. (GR)	2010-12-29	—	—	WO	disclosed