Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PER2 | O15055 | 2/20 | 0.43 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701126 | 0.82 | LMNA (0.66) | MAPTLMNARECQLMEN1KMT2A | |
| SCHEMBL16709560 | 0.79 | DNM1 (0.60) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL409553 | 0.76 | TSPO (0.59) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL16923670 | 0.75 | LMNA (0.62) | MAPTLMNARECQLMEN1KMT2A | |
| SCHEMBL16923758 | 0.75 | LMNA (0.62) | MAPTLMNARECQLMEN1KMT2A | |
| SCHEMBL14689199 | 0.74 | LMNA (0.68) | MAPTLMNARECQLMEN1KMT2A | |
| SCHEMBL17484540 | 0.73 | HSD17B10 (0.49) | MAPTLMNARECQLMEN1KMT2A | |
| SCHEMBL16923623 | 0.73 | LMNA (0.60) | MAPTLMNARECQLMEN1KMT2A | |
| SCHEMBL407490 | 0.72 | TSPO (0.70) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL9691293 | 0.71 | CNR1 (0.58) | MAPTLMNAMEN1KMT2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415289-A | Pro-neurogenic compounds | UNIV TEXAS | 2013-11-27 | — | — | CN | disclosed |