Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572229 | 0.85 | OPRM1 (0.55) | MEN1KMT2AOPRM1OPRL1GRIN2B | |
| Hydrochloric Acid SCHEMBL573397 | 0.84 | OPRM1 (0.56) | MEN1KMT2AOPRM1OPRL1GRIN2B | |
| SCHEMBL662411 | 0.79 | GRIN2B (0.76) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL3760581 | 0.76 | TAAR1 (0.75) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL3907332 | 0.76 | TAAR1 (0.81) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL8949095 | 0.75 | TAAR1 (0.61) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL24767088 | 0.74 | TAAR1 (0.84) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL25002632 | 0.74 | TAAR1 (0.84) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL21792273 | 0.74 | TAAR1 (0.84) | TAAR1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL22216853 | 0.74 | TAAR1 (0.84) | TAAR1MEN1KMT2AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103168032-A | Benzimidazole and azabenzimidazole compounds that inhibit anaplastic lymphoma kinase | AMGEN INC | 2013-06-19 | — | — | CN | disclosed |