Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | RAD52 | P43351 | 1/20 | 0.78 |
| ▸ | UBE2N | P61088 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stilbamidine SCHEMBL3934275 | 1.00 | POLB (0.78) | POLBKDM4EMAPTRAD52UBE2N | |
| Hydroxystilbamidine SCHEMBL554644 | 0.88 | POLB (1.00) | POLBKDM4EMAPTRAD52UBE2N | |
| Hydroxystilbamidine SCHEMBL10621745 | 0.88 | POLB (1.00) | POLBKDM4EMAPTRAD52UBE2N | |
| Hydroxystilbamidine SCHEMBL10621740 | 0.88 | POLB (1.00) | POLBKDM4EMAPTRAD52UBE2N | |
| Benzamidine SCHEMBL27925636 | 0.81 | POLB (0.61) | POLBKDM4EMAPTRAD52UBE2N | |
| Benzamidine SCHEMBL5522150 | 0.81 | POLB (0.61) | POLBKDM4EMAPTRAD52UBE2N | |
| SCHEMBL5522149 | 0.81 | POLB (0.74) | POLBKDM4EMAPTRAD52UBE2N | |
| Stilbamidine SCHEMBL208655 | 0.78 | PRMT1 (1.00) | ALDH1A1PRMT1PRMT5HPGDCYP2C19 | |
| Stilbamidine SCHEMBL889782 | 0.78 | PRMT1 (1.00) | ALDH1A1PRMT1PRMT5HPGDCYP2C19 | |
| Propamidine SCHEMBL293021 | 0.77 | ALDH1A1 (0.92) | POLBKDM4EMAPTALDH1A1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376074-B1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2019-03-13 | — | — | EP | disclosed |