Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | GMNN | O75496 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | THPO | P40225 | 1/20 | 0.74 |
| ▸ | MTOR | P42345 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.61 |
| ▸ | F2 | P00734 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propamidine SCHEMBL293021 | 0.86 | ALDH1A1 (0.92) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL27719324 | 0.85 | ALDH1A1 (1.00) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Hexamidine SCHEMBL128384 | 0.85 | ALDH1A1 (1.00) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL33615 | 0.85 | ALDH1A1 (1.00) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Hexamidine SCHEMBL985947 | 0.85 | ALDH1A1 (1.00) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL19462606 | 0.84 | ALDH1A1 (0.97) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL5014184 | 0.84 | ALDH1A1 (0.97) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL2658011 | 0.83 | ALDH1A1 (0.95) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL23063972 | 0.82 | ALDH1A1 (0.92) | POLBALDH1A1LMNARAB9ASMN1; SMN2 | |
| Benzamidine SCHEMBL5522150 | 0.81 | POLB (0.61) | POLBALDH1A1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | claimed |
| US-20250312349-A1 | COMPOSITION AND METHODS OF TREATING INTRACELLULAR PATHOGEN INFECTION | UNIV HOSPITALS CLEVELAND MEDICAL CENTER (US) | 2025-10-09 | — | — | US | disclosed |
| US-11566012-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD (AU) | 2023-01-31 | — | — | US | disclosed |
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |
| US-20210009552-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-01-14 | — | — | US | disclosed |
| US-10829468-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-11-10 | — | — | US | disclosed |
| US-20200290990-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-09-17 | — | — | US | disclosed |
| US-10752606-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-08-25 | — | — | US | disclosed |
| EP-1601249-B1 | 1-N-ARYLPYRAZOLE DERIVATIVES FOR INTERRUPTING THE TRANSMISSION OF MOSQUITO-BORNE DISEASES | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2020-07-08 | — | — | EP | disclosed |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | disclosed |
| EP-1601249-A1 | 1-N-ARYLPYRAZOLE DERIVATIVES IN PREVENTION OF ARTHROPOD-BORNE AND MOSQUITO-BORNE DISEASES | Merial Limited (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2005009129-A1 | 1-N-ARYLPYRAZOLE DERIVATIVES IN PREVENTION OF ARTHROPOD-BORNE AND MOSQUITO-BORNE DISEASES | MERIAL LIMITED (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20040167175-A1 | 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases | MERIAL LIMITED, REGISTERED IN ENGLAND AND WALES NO. 3332751 AND DOMESTICATED IN DELAWARE, USA AS MERIAL LLC, WITH A PLACE OF BUSINESS AT 3239 SATELLITE BLVD., DULUTH, GA 30096-4640 (GB) | 2004-08-26 | — | — | US | disclosed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5610179-A | TELLURIUM COMPOUND | SREDNI BENJAMIN (IL) | 1997-03-11 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566012-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
| US-20040167175-A1 | 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases | NAT1, PON1, AANAT | POLB 2826/4885ALDH1A1 177/4885LMNA 3819/4885 |
| US-20200290990-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
| US-20210009552-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
| US-10829468-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
| US-10752606-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | POLB 3872/4885ALDH1A1 840/4885LMNA 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.