Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203519 | 0.82 | BCAT2 (0.59) | IKBKBBCAT2KMT2AATMPARP1 | |
| SCHEMBL29940950 | 0.82 | BCAT2 (0.59) | IKBKBBCAT2KMT2AATMPARP1 | |
| SCHEMBL3234101 | 0.78 | BCAT2 (0.59) | IKBKBBCAT2KMT2AATMPDK2 | |
| SCHEMBL27656527 | 0.77 | AR (0.51) | IKBKBBCAT2SCN9APDK2CHEK1 | |
| SCHEMBL7806602 | 0.77 | PDK2 (0.46) | IKBKBBCAT2PDK2BACE1 | |
| SCHEMBL5924975 | 0.76 | ALDH1A1 (0.57) | PDK2CYP2A6 | |
| SCHEMBL27474391 | 0.75 | BCAT2 (0.56) | IKBKBBCAT2KMT2AATMPDK2 | |
| SCHEMBL31509740 | 0.75 | PPM1B (0.51) | KMT2AMAP4K4CYP2A6BACE1JAK2 | |
| SCHEMBL13522902 | 0.75 | PPM1B (0.51) | KMT2AMAP4K4CYP2A6BACE1JAK2 | |
| SCHEMBL2688812 | 0.75 | CHEK2 (0.58) | IKBKBBCAT2SCN9AMAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429583-A | Triazole derivatives as WNT signaling pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF | 2013-12-04 | — | — | CN | disclosed |