Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 4/20 | 0.45 |
| ▸ | RORC | P51449 | 4/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635470 | 0.82 | BCAT2 (0.63) | PDK2RORBRORCIKBKBBCAT2 | |
| SCHEMBL28856804 | 0.79 | BCAT2 (0.45) | PDK2BCAT2ALOX5APFEN1EIF4E | |
| SCHEMBL27656528 | 0.79 | BCAT2 (0.54) | PDK2RORBRORCIKBKBBCAT2 | |
| SCHEMBL5143960 | 0.78 | PARP1 (0.56) | PDK2BCAT2SCN9AAKR1C3AKR1C2 | |
| SCHEMBL30608075 | 0.78 | PARP1 (0.56) | PDK2BCAT2SCN9AAKR1C3AKR1C2 | |
| SCHEMBL31583298 | 0.78 | BCAT2 (0.51) | PDK2RORBRORCBCAT2CHEK1 | |
| SCHEMBL5131379 | 0.78 | PDK2 (0.49) | PDK2RORCMAPK14AKR1C3AKR1C2 | |
| SCHEMBL27925864 | 0.77 | IKBKB (0.52) | PDK2IKBKBBCAT2CHEK1SCN9A | |
| SCHEMBL6187171 | 0.77 | BCAT2 (0.50) | PDK2RORBRORCBCAT2CHEK1 | |
| SCHEMBL1203519 | 0.76 | BCAT2 (0.59) | IKBKBBCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102793692-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP | 2012-11-28 | — | — | CN | claimed |
| CN-1826120-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2006-08-30 | — | — | CN | claimed |