Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.87 |
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.73 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.73 |
| ▸ | NAMPT | P43490 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TNF | P01375 | 1/20 | 0.66 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665029 | 0.87 | EPHX2 (0.76) | EPHX2RAB9ANPC1NAMPTLMNA | |
| SCHEMBL12977899 | 0.86 | RAB9A (0.67) | EPHX2RAB9ANPC1CYP11B1CYP11B2 | |
| SCHEMBL792186 | 0.86 | MEN1 (0.68) | EPHX2RAB9ANPC1CYP11B1CYP11B2 | |
| SCHEMBL29737572 | 0.86 | MEN1 (0.68) | EPHX2RAB9ANPC1CYP11B1CYP11B2 | |
| SCHEMBL28007807 | 0.85 | NAMPT (0.81) | RAB9ANPC1CYP11B1CYP11B2NAMPT | |
| SCHEMBL30772272 | 0.85 | EPHX2 (0.87) | EPHX2RAB9ANPC1NAMPTMEN1 | |
| SCHEMBL14082554 | 0.85 | EPHX2 (0.73) | EPHX2RAB9ANPC1NAMPTLMNA | |
| SCHEMBL789622 | 0.85 | RAB9A (0.78) | EPHX2RAB9ANPC1KMT2AGAA | |
| SCHEMBL789916 | 0.85 | EPHX2 (0.65) | EPHX2RAB9ANPC1CYP11B1CYP11B2 | |
| SCHEMBL30582756 | 0.84 | CYP11B1 (1.00) | RAB9ANPC1CYP11B1CYP11B2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189061-A | 4- (methylaminophenoxy) pyrdin- 3 - yl - benzamide derivatives for treating cancer | OTSUKA PHARMA CO LTD | 2013-07-03 | — | — | CN | claimed |
| WO-2023186102-A1 | NAV1.8 INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-103189061-A | 4- (methylaminophenoxy) pyrdin- 3 - yl - benzamide derivatives for treating cancer | OTSUKA PHARMA CO LTD | 2013-07-03 | — | — | CN | disclosed |