Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.73 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.70 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167081 | 0.89 | NAMPT (1.00) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL27890956 | 0.88 | NAMPT (0.97) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL1571386 | 0.87 | LMNA (1.00) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL3642636 | 0.86 | NAMPT (0.81) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL5435462 | 0.86 | NAMPT (0.76) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL27927283 | 0.85 | EPHX2 (0.87) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL5450085 | 0.85 | NAMPT (0.73) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL95793 | 0.85 | NAMPT (0.73) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL12078341 | 0.85 | NAMPT (0.77) | NAMPTLMNAHIF1ACYP11B1CYP11B2 | |
| SCHEMBL30582756 | 0.85 | CYP11B1 (1.00) | NAMPTLMNAHIF1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801322-B | Kinase inhibitors for the treatment of central and peripheral nervous system disorders | 迈阿密大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-104447518-A | Synthesis method for flexible dipyridine derivative 6-bromine-2-pyridine methylenepyridine | HARBIN INST OF TECHNOLOGY | 2015-03-25 | — | — | CN | disclosed |