Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956059 | 0.78 | KDM4E (0.32) | — | |
| SCHEMBL27955366 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL21763267 | 0.74 | TTR (0.42) | XDHTTRALB | |
| SCHEMBL21212728 | 0.71 | TTR (0.40) | XDHTTRALB | |
| SCHEMBL27943551 | 0.71 | TRPV4 (0.39) | — | |
| SCHEMBL25566981 | 0.67 | XDH (0.35) | XDHTTRALB | |
| SCHEMBL25567065 | 0.67 | XDH (0.35) | XDHTTRALB | |
| SCHEMBL28448609 | 0.67 | — | — | |
| SCHEMBL31085445 | 0.65 | KDM4E (0.52) | XDHTTRALB | |
| SCHEMBL14055264 | 0.65 | KDM4E (0.52) | XDHTTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159741-B | The preparation of one class tyrosine kinase inhibitor and purposes | 天津市国际生物医药联合研究院 | 2016-08-24 | — | — | CN | disclosed |
| CN-103159741-A | Preparation and application of novel tyrosine kinase inhibitor | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2013-06-19 | — | — | CN | disclosed |