Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681698 | 0.78 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL27956059 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1USP2CYP3A4 | |
| SCHEMBL5842498 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL27927643 | 0.75 | XDH (0.36) | — | |
| SCHEMBL5843665 | 0.75 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL1097316 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL3226130 | 0.72 | — | — | |
| SCHEMBL27943551 | 0.71 | TRPV4 (0.39) | KDM4ECYP3A4 | |
| SCHEMBL11402674 | 0.70 | — | — | |
| SCHEMBL119203 | 0.69 | TSHR (0.50) | TSHRKDM4EALDH1A1USP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103751943-A | Fire extinguishing composition containing nitrogenous organic compound | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-04-30 | — | — | CN | claimed |
| CN-104877127-B | A kind of eight arms polyethyleneglycol derivative, preparation method and its bio-related substance of modification | 厦门赛诺邦格生物科技股份有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-104877127-A | Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative | XIAMEN SINOPEG BIOTECH CO LTD | 2015-09-02 | — | — | CN | disclosed |
| CN-103751943-A | Fire extinguishing composition containing nitrogenous organic compound | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-04-30 | — | — | CN | disclosed |