SCHEMBL6422815

SCHEMBL6422815

COc1c(F)cc(C(=O)O)c(F)c1F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PKM P14618 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
CYP2C9 P11712 2/20 0.38
CYP1A2 P05177 1/20 0.38
GFER P55789 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.38
TUBB1 Q9H4B7 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424948 0.89 HSD17B10 (0.44) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL28583415 0.85 MEN1 (0.42) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL27879635 0.85 MAPT (0.46) HSD17B10LMNAMAPK1HTTRAB9A
SCHEMBL5622209 0.85 HTT (0.40) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL5272363 0.85 ALDH1A1 (0.39) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL1617264 0.85 HSD17B10 (0.49) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL607945 0.85 HSD17B10 (0.44) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL27929289 0.84 HSD17B10 (0.49) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL20551451 0.84 ALDH1A1 (0.41) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL27875674 0.84 HSD17B10 (0.41) HSD17B10MEN1KMT2ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406469-A For extraction from aqueous streamsGet C1To C4Quaternary arylcarboxylate salt compositions of carboxylic acids 伊士曼化工公司 2017-11-28 CN claimed
US-9040268-B2 Method for controlling undesirable byproducts formation caused by contaminating organisms in the production of ethanol from syngas COSKATA, INC. (US) 2015-05-26 US claimed
EP-2758540-A1 METHOD FOR CONTROLLING UNDESIRABLE BYPRODUCTS FORMATION CAUSED BY CONTAMINATING ORGANISMS IN THE PRODUCTION OF ETHANOL FROM SYNGAS Coskata Energy Inc. (US) 2014-07-30 EP claimed
WO-2013043513-A1 METHOD FOR CONTROLLING UNDESIRABLE BYPRODUCTS FORMATION CAUSED BY CONTAMINATING ORGANISMS IN THE PRODUCTION OF ETHANOL FROM SYNGAS COSKATA, INC. (US) 2013-03-28 WO claimed
US-20130071897-A1 METHOD FOR CONTROLLING UNDESIRABLE BYPRODUCTS FORMATION CAUSED BY CONTAMINATING ORGANISMS IN THE PRODUCTION OF ETHANOL FROM SYNGAS COSKATA, INC. (US) 2013-03-21 US claimed
EP-4565581-A1 PYRAZOLO PESTICIDAL COMPOUNDS BASF SE (DE) 2025-06-11 EP disclosed
CN-115850202-B Small molecule inhibitor of frizzled receptor 7 and preparation method and application thereof 上海科技大学 2024-06-25 CN disclosed
US-20240083853-A1 HSD17B13 INHIBITORS AND USES THEREOF FL2022-001, INC. 2024-03-14 US disclosed
WO-2024028243-A1 PYRAZOLO PESTICIDAL COMPOUNDS BASF SE (DE) 2024-02-08 WO disclosed
CN-116600801-A HSD17B13 inhibitors and uses thereof FL2022-001公司 2023-08-15 CN disclosed
EP-4221701-A1 HSD17B13 INHIBITORS AND USES THEREOF FL2022-001, Inc. (US) 2023-08-09 EP disclosed
WO-2022072491-A1 HSD17B13 INHIBITORS AND USES THEREOF METACRINE, INC. (US) 2022-04-07 WO disclosed
US-5525258-A LOW VISCOSITY, SHORT RESPONSE TIME HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-11 US disclosed
US-5430173-A Process for preparing alkyl 3-hydroxy-2, 4, 5-trifluorobenzoates and/or alkyl 3-alkoxy-2, 4, 5-trifluorobenzoates HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-04 US disclosed
EP-0645366-A1 Process for the preparation of alkyle esters of 3-hydroxy-2,4,5-trifluoro benzoic acid and/or of 3-alcoxy-2,4,5 trifluoro benzoic acid HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-29 EP disclosed
CN-1100261-A Herbicides RHONE POULENC AGRICULTURE (GB) 1995-03-22 CN disclosed
CN-1027692-C Process for producing dienamide derivative ROUSSEL UCLAF CO (FR) 1995-02-22 CN disclosed
CN-1089258-A New herbicides RHONE POULENC AGRICULTURE (GB) 1994-07-13 CN disclosed
EP-0602596-A1 Trifluorophenylene compounds, process for their preparation and their use in liquid crystalline mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-22 EP disclosed
CN-1045576-A Pesticide WELLCOME FOUND (GB) 1990-09-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240083853-A1 HSD17B13 INHIBITORS AND USES THEREOF HSD17B3, HSD17B11, HSD17B1 HSD17B10 12/4885MEN1 3193/4885KMT2A 3736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.