Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422815 | 0.84 | HSD17B10 (0.44) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL28583415 | 0.81 | MEN1 (0.42) | HSD17B10LMNAHTTTDP1MAPK1 | |
| SCHEMBL28424948 | 0.80 | HSD17B10 (0.44) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL27929289 | 0.79 | HSD17B10 (0.49) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL20551451 | 0.79 | ALDH1A1 (0.41) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL27540803 | 0.78 | HSD17B10 (0.50) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL7595186 | 0.77 | KEAP1 (0.42) | TPMTSOS1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL27879635 | 0.77 | MAPT (0.46) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL607945 | 0.77 | HSD17B10 (0.44) | HSD17B10TPMTLMNAHTTTDP1 | |
| SCHEMBL1617264 | 0.77 | HSD17B10 (0.49) | HSD17B10TPMTLMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690194-A | Preparation method of 3-cyclopropylmethoxy-4-difluoromethoxy-benzoic acid | SHANGHAI TONGYUAN BIOTECHNOLOGY CO LTD | 2012-09-26 | — | — | CN | claimed |
| CN-103467294-A | 3-bromo-4-difluoromethoxy methyl benzoate preparation method | SHANGHAI INST PHARM INDUSTRY | 2013-12-25 | — | — | CN | disclosed |