Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21845156 | 1.00 | HTR2A (0.43) | HTR2ASIGMAR1ANPEPKDM4EALDH1A1 | |
| SCHEMBL9493200 | 0.80 | PDPK1 (0.43) | HTR2AKDM1APDPK1 | |
| SCHEMBL24388765 | 0.80 | HTR2A (0.41) | HTR2ASIGMAR1ANPEPKDM4EALDH1A1 | |
| SCHEMBL23811378 | 0.80 | HTR2A (0.41) | HTR2ASIGMAR1ANPEPKDM4EALDH1A1 | |
| SCHEMBL21887274 | 0.77 | HTR2A (0.41) | HTR2ASIGMAR1ANPEPKDM4EALDH1A1 | |
| SCHEMBL24389159 | 0.77 | HTR2A (0.38) | HTR2ASIGMAR1KDM1A | |
| SCHEMBL9247940 | 0.77 | MAOB (0.40) | HTR2ASIGMAR1KDM1A | |
| SCHEMBL2582726 | 0.77 | SIGMAR1 (0.41) | SIGMAR1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1745011 | 0.75 | ALOX15 (0.44) | SIGMAR1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL700442 | 0.75 | SIGMAR1 (0.40) | SIGMAR1KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| CN-101489984-B | Aminoindan derivative or salt thereof | ASTELLAS PHARMA INC | 2013-04-03 | — | — | CN | disclosed |
| US-20100167925-A1 | Substituted Azolin-2-yl-Amino Compounds | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| CN-101489984-A | Aminoindan derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-07-22 | — | — | CN | disclosed |
| EP-2051970-A1 | SUBSTITUTED AZOLIN-2-YL-AMINO COMPOUNDS | BASF SE (DE) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008017649-A1 | SUBSTITUTED AZOLIN-2-YL-AMINO COMPOUNDS | BASF SE (DE) | 2008-02-14 | — | — | WO | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-6139769-A | CONTACTING A SUBSTRATE WITH AN AQUEOUS SOLUTION COMPRISING A PEROXIDE AND A METAL COMPLEX BLEACH ACTIVATOR FOR LAUNDERING AND CLEANING | CLARIANT GMBH (DE) | 2000-10-31 | — | — | US | disclosed |
| US-5998645-A | LAUNDERING DETERGENTS; CLEANING COMPOUNDS | CLARIANT GMBH (DE) | 1999-12-07 | — | — | US | disclosed |
| US-5969171-A | Metal complexes as bleach activators | CLARIANT GMBH (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-5246915-A | Herbicides | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-09-21 | — | — | US | disclosed |
| US-4994103-A | Herbicides; rice, corn | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-19 | — | — | US | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| US-4878940-A | SELECTIVE, FOR USE WITH CROPS | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-11-07 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |
| EP-0289066-A1 | 1,5-Substituted 1H-imidazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167925-A1 | Substituted Azolin-2-yl-Amino Compounds | CBR3, NR2C2, HRH3 | HTR2A 2704/4885SIGMAR1 1391/4885ANPEP 1763/4885 |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | HTR2A 2824/4885SIGMAR1 1445/4885ANPEP 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.