Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22845074 | 0.75 | GABRA1 (0.48) | GABRA1GABRB2TRPA1 | |
| SCHEMBL45861 | 0.73 | GABRA1 (0.68) | GABRA1GABRB2TRPA1FEN1ESR1 | |
| SCHEMBL21343570 | 0.72 | GABRA1 (0.45) | GABRA1GABRB2FEN1ESR1ESR2 | |
| SCHEMBL29256509 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2FEN1ESR1ESR2 | |
| SCHEMBL27434956 | 0.69 | PRKCI (0.42) | — | |
| SCHEMBL5676415 | 0.68 | GABRA1 (0.54) | GABRA1GABRB2TRPA1ESR1ESR2 | |
| SCHEMBL29719025 | 0.65 | GABRA1 (0.56) | GABRA1GABRB2ESR1ESR2 | |
| SCHEMBL2475390 | 0.65 | GABRA1 (0.56) | GABRA1GABRB2ESR1ESR2 | |
| SCHEMBL14365507 | 0.65 | GABRA1 (0.50) | GABRA1GABRB2FEN1ESR1ESR2 | |
| SCHEMBL5196215 | 0.63 | PRKCI (0.57) | GABRA1GABRB2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169318-A | Low density all water blown polyurethane rigid foams | DOW GLOBAL TECHNOLOGIES INC | 2014-11-26 | — | — | CN | disclosed |
| CN-103261258-A | Polyurethane and polyisocyanurate foams | DOW GLOBAL TECHNOLOGIES INC | 2013-08-21 | — | — | CN | disclosed |