Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859471 | 0.90 | GNAI3 (0.50) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL12817476 | 0.89 | GNAI3 (0.57) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL12617222 | 0.85 | ITGB3 (0.52) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL13347933 | 0.85 | GNAI3 (0.49) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| Hydrochloric Acid SCHEMBL2423075 | 0.83 | GNAI3 (0.51) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL6855190 | 0.83 | NCF1 (0.48) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL2419318 | 0.83 | GNAI3 (0.47) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL26723251 | 0.82 | GNAI3 (0.46) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| Hydrochloric Acid SCHEMBL30412623 | 0.82 | GNAI3 (0.50) | GNAI3GNAO1GNAI1NCF1ITGB3 | |
| SCHEMBL12254583 | 0.80 | GNAI3 (0.45) | GNAI3GNAO1GNAI1NCF1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679410-B | 2-[(2-substituted)-ind0lizin-3-yl]-2-oxo-acetamide derivatives as antifungal agents | F2G LTD | 2013-11-27 | — | — | CN | disclosed |