Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.60 |
| ▸ | PIM1 | P11309 | 2/20 | 0.60 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.60 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934288 | 0.84 | CA12 (0.66) | GPR35SLC16A3MAOBMEN1POLB | |
| SCHEMBL28807108 | 0.81 | GPR35 (0.60) | GPR35PIM1PIM2TP53MAPT | |
| SCHEMBL28805354 | 0.81 | CNR2 (0.66) | GPR35TP53MAPTMAOBMAOA | |
| SCHEMBL27915787 | 0.80 | CNR2 (0.66) | GPR35TP53MAPTMAOBMAOA | |
| SCHEMBL22041627 | 0.79 | ALDH1A1 (0.58) | GPR35PIM1TP53MAPTMAOB | |
| SCHEMBL27934335 | 0.79 | CNR2 (0.65) | GPR35TP53MAPTMAOBMAOA | |
| SCHEMBL5839199 | 0.77 | FOLH1 (0.56) | PIM1PIM2POLBALDH1A1FOLH1 | |
| SCHEMBL3080344 | 0.76 | GPR35 (1.00) | GPR35MAPTMAOBMAOAALDH1A1 | |
| SCHEMBL29376304 | 0.75 | FOLH1 (0.53) | SLC16A3MAOBMEN1POLBKMT2A | |
| SCHEMBL22412608 | 0.75 | FOLH1 (0.53) | SLC16A3MAOBMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-A | 3-substituted coumarin derivative and use thereof | UNIV ZHEJIANG | 2013-08-28 | — | — | CN | disclosed |