Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384788 | 0.81 | ESR1 (0.50) | POLBALDH1A1HSD17B10LMNARECQL | |
| SCHEMBL28649489 | 0.81 | ALDH1A1 (0.46) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL2696214 | 0.78 | POLB (0.61) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL5229558 | 0.76 | HTT (0.58) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL8558804 | 0.76 | HTT (0.55) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| Cyclopropane SCHEMBL27934850 | 0.73 | HTT (0.51) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL11521611 | 0.70 | KMT2A (0.49) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL10211704 | 0.69 | ALDH1A1 (0.51) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL9872251 | 0.69 | CYP3A4 (0.45) | HTTALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL26348347 | 0.68 | RECQL (0.46) | HTTPOLBALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103278468-A | Creatinine detection reagent | NINGBO MEDICAL BIOLOG TECHNOLOGY CO LTD | 2013-09-04 | — | — | CN | disclosed |