Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PER2 | O15055 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL27934850 | 0.95 | HTT (0.51) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL2696214 | 0.84 | POLB (0.61) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL5229558 | 0.83 | HTT (0.58) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL11441700 | 0.81 | HSD17B10 (0.44) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL6017430 | 0.80 | ESR1 (0.59) | ALDH1A1HSD17B10POLBGLALMNA | |
| SCHEMBL5892163 | 0.80 | ESR1 (0.59) | ALDH1A1HSD17B10POLBGLALMNA | |
| SCHEMBL27934849 | 0.76 | HTT (0.49) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL28649489 | 0.75 | ALDH1A1 (0.46) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL5157417 | 0.75 | ESR1 (0.36) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL9314947 | 0.74 | TP53 (0.49) | HTTALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5755231-A | Test strip including integral specimen flow retarding structure | PLUS BIO, INC. (US) | 1998-05-26 | — | — | US | claimed |
| WO-1998000703-A1 | TEST STRIP INCLUDING INTEGRAL SPECIMEN FLOW RETARDING STRUCTURE | PLUS BIO, INC. (US) | 1998-01-08 | — | — | WO | claimed |
| US-5755231-A | Test strip including integral specimen flow retarding structure | PLUS BIO, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1998000703-A1 | TEST STRIP INCLUDING INTEGRAL SPECIMEN FLOW RETARDING STRUCTURE | PLUS BIO, INC. (US) | 1998-01-08 | — | — | WO | disclosed |