SCHEMBL28649489

SCHEMBL28649489

CCN(c1cccc(C)c1)S(=O)(=O)OCC(C)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
HTT P42858 2/20 0.45
LMNA P02545 5/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MAPT P10636 2/20 0.45
POLB P06746 3/20 0.44
GLA P06280 2/20 0.44
GAA P10253 2/20 0.43
PER2 O15055 1/20 0.42
CRY1 Q16526 1/20 0.42
CRY2 Q49AN0 1/20 0.42
TP53 P04637 1/20 0.41
NPC1 O15118 1/20 0.40
TSHR P16473 1/20 0.40
RECQL P46063 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31196851 0.86 MEN1 (0.41) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL31195747 0.85 MEN1 (0.40) ALDH1A1HPGDHSD17B10ALOX15NPSR1
SCHEMBL27934849 0.81 HTT (0.49) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL8558804 0.75 HTT (0.55) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL2696214 0.74 POLB (0.61) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL5229558 0.72 HTT (0.58) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL11735905 0.72 ALDH1A1 (0.45) ALDH1A1HPGDHSD17B10ALOX15LMNA
Cyclopropane SCHEMBL27934850 0.72 HTT (0.51) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL1802310 0.70 TP53 (0.45) ALDH1A1HPGDHSD17B10ALOX15HTT
SCHEMBL10909573 0.69 TP53 (0.44) ALDH1A1HPGDHSD17B10ALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115248206-B Cholesterol detection kit, preparation application and sample analysis method 深圳迈瑞生物医疗电子股份有限公司 2025-06-03 CN disclosed
CN-109580504-B Lipoprotein cholesterol determination reagent and kit 东软威特曼生物科技(南京)有限公司 2021-10-26 CN disclosed